Muscle MRI Biomarkers for Duchenne Muscular Dystrophy (DMD)
An overview of the use of MR imaging biomarkers for Duchenne Muscular Dystrophy (DMD) in research studies & clinical trials.
[18F]DOPA PET in Parkinson’s Disease Clinical Trials
How [18F]DOPA PET is used to monitor disease progression & response to therapeutic intervention in Parkinson’s disease & movement disorders clinical trials.
Spinocerebellar Ataxia Clinical Trials & Imaging Biomarkers
An overview of structural MRI, DTI and MRS imaging biomarkers to monitor disease progression in spinocerebellar ataxia clinical trials.
PET Imaging in Huntington’s Disease Clinical Trials
An overview of the use of PET imaging biomarkers for Huntington’s disease (HD) clinical trials.
Neuroimaging Biomarkers for Tuberous Sclerosis Complex (TSC)
Overview of brain structural MRI and diffusion-weighted imaging biomarkers to monitor efficacy of disease-modifying therapeutics in clinical trials of TSC.
MRI Biomarkers in Clinical Trials of Huntington’s Disease
An overview of the use of structural and diffusion MRI imaging biomarkers for Huntington’s disease (HD) clinical trials.
Modeling Protein Misfolding in Neurological Diseases
Computational modeling of protein misfolding mechanisms in neurodegeneration and the application to discovery & development of disease-modifying therapeutics.
Imaging Biomarkers for Friedreich’s Ataxia Clinical Trials
An overview of the use of MRI and DTI imaging biomarkers for Friedreich’s ataxia (FRDA) in research studies & multi-center clinical trials.
Neuroimaging in Frontotemporal Dementia & Clinical Trials
The utility of MRI & PET imaging biomarkers in our understanding of Frontotemporal Dementia (FTD) variants, and their use as endpoints in FTD clinical trials.
MRI Gadolinium-Enhancing Lesions in MS Clinical Trials
How gadolinium (Gd) enhancing lesions are used to track disease progression & response to therapeutic intervention in multiple sclerosis (MS) clinical trials.
MRI in Clinical Trials of Multiple System Atrophy (MSA)
This resource provides an overview of the utility of volumetric MRI and diffusion-weighted imaging (DWI) as biomarkers in research studies of MSA.
Imaging Biomarkers for Progressive Supranuclear Palsy (PSP)
An overview of the various brain imaging methods (MRI, PET, SPECT) available to assess efficacy of disease-modifying therapeutics in clinical trials of PSP.
