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Table of Contents

Table of Contents

Abstract
01. Presentation Overview
Presentation
01. Introduction02. CDCA Methods 103. CDCA Methods 204. CDCA Methods 305. CDCA Methods 406. CDCA Methods 507. CDCA - Spatial Loadings08. CDCA - Scores09. Cross-Eigenimages10. Amyloid Cross-Eigenimages 111. Tau Cross-Eigenimages 112. Amyloid Cross-Eigenimages 213. Tau Cross-Eigenimages 214. Summary
Spatial loadings for the first canonical distance correlation component.

Spatial loadings for the first canonical distance correlation component. The strongest weights in the β-amyloid eigenimage are spread over large areas of the cortex, while the strongest weights corresponding to the tau map are localized within the lateral inferior temporal gyri and fusiform gyri.

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A Canonical Distance Correlation Analysis was applied to a matched sample of β-amyloid and tau PET images.

The first canonical component accounted for 26.31% of the total co-variability between β-amyloid and tau.

Panel A in the figure shows the spatial loadings corresponding to β-amyloid, where the strongest positive weights appeared spread over the medial prefrontal and posterior cingulate cortices, precuneus, lateral inferior temporal gyri, and fusiform gyri.

Panel B in the figure shows the spatial loadings corresponding to tau, where the strongest positive loads are localized within the lateral inferior temporal gyri and the bilateral fusiform gyrus.

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