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Table of Contents

Table of Contents

Abstract
01. Presentation Overview
Presentation
01. Introduction02. CDCA Methods 103. CDCA Methods 204. CDCA Methods 305. CDCA Methods 406. CDCA Methods 507. CDCA - Spatial Loadings08. CDCA - Scores09. Cross-Eigenimages10. Amyloid Cross-Eigenimages 111. Tau Cross-Eigenimages 112. Amyloid Cross-Eigenimages 213. Tau Cross-Eigenimages 214. Summary
Spatial distribution of the amyloid cross-eigenimage in low and high β-amyloid  groups.

Spatial distribution of the amyloid cross-eigenimage in low and high β-amyloid  groups. The tau scores appear to have stronger distance-correlation with β-amyloid for the Aβ High group, particularly in the lateral inferior temporal gyri.

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The Canonical Distance Correlation Analysis was re-assessed for the aggregation of subjects according to their β-amyloid status based on tracer uptake in an AD-signature composite region-of-interest.

The first canonical component accounted for 11.75% and 16.75% of the total co-variability in the low and high β-amyloid groups, respectively.

The figure reveals that the β-amyloid cross-eigenimage shows stronger distance-correlations values for the high β-amyloid group, particularly in areas covering the lateral temporal gyri.

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